|Statement||chairman, P.B. Fernandes ; section chairmen, D.T.W. Chu ... [et al. ; edited by P.B. Fernandes].|
|Contributions||Chu, D. T. W., Fernandes, P. B.|
|LC Classifications||RM666.Q55 I58 1989|
|The Physical Object|
|Pagination||x, 446 p. :|
|Number of Pages||446|
New quinolones are continually being developed as bacterial species develop resistance to existing quinolones. This book presents the most current information available in our continual struggle to conquer disease. Over time, bacteria become resistant to medicines that are used to combat them.5/5(1). The Quinolones covers reviews on the history, chemistry and mechanism of action, in vitro properties, pharmacokinetics, clinical overview, toxicity, adverse effects and drug interactions, and future prospects of the 4-quinolones. The book discusses the microbiology of quinolones, particularly with consideration of the development of resistance, pharmacology, toxicology, and clinical Edition: 1. and aminoglycosides, the quinolones are not predictably synergistic. 1 Although the effects of most combinations are indifferent or additive, ciprofloxacin (Cipro) and rifampin (Rifadin)Cited by: Quinolones And Fluoroquinolones: Quinolones And Fluoroquinolones The quinolones (Qs) and fluoroquinolones (FQs) are a family of broad-spectrum synthetic antimicrobial agents. The parent of the group is nalidixic acid, which was introduced in The fluoroquinolones have a fluoro group attached the central ring system.
Quinolones are a type of antibiotic. Antibiotics kill or inhibit the growth of bacteria. There are five different quinolone classes. In addition, another class of antibiotic, called fluoroquinolones, were derived from quinolones by modifying their structure with fluorine. Quinolones and fluoroquinolones have many things in common, but also a few differences such as what organisms they are effective . ALPHABETICAL LISTINGS OF QUINOLONE DRUGS. This is not a complete List of Quinolones and Fluoroquinolones that have been in existence. There are thousands of quinolones and related drugs, often with different generic names for the same drug, so be aware of the drugs that you are taking and look them up yourself if you have experienced toxicity from these drugs. With the increasing number of available quinolone antibiotics, prescribing these drugs has become a challenge. Compared with older quinolones such as norfloxacin (Noroxin) and ciprofloxacin (Cipro Cited by: The quinolone class is one of the most important classes of antibiotics identified in the past 50 years . The discovery of fluoroquinolones in the s constituted a breakthrough due to their excellent broad-spectrum activity that includes Gram-negative pathogens.
The third edition of Quinolone Antimicrobial Agents nicely addresses these advances. The book is organized into four sections, each containing chapters written by leading experts. Mechanisms and Spectrum of Activity and Resistance, the first major section, explores the basic biology of the quinolone Cited by: The fluoroquinolones are active against intracellular pathogens, including, eg, Brucella spp. Quinolones also have significant activity against Mycoplasma and Chlamydia spp. Obligate anaerobes tend to be resistant to most quinolones, as are most enterococci (previously group D Streptococcus spp (Enterococcus faecalis and Enterococcus faecium). New quinolones are continually being developed as bacterial species develop resistance to existing quinolones. This book presents the most current information available in our continual struggle to . The fluoroquinolones are indicated for treatment of several bacterial infections, including bacterial bronchitis, pneumonia, sinusitis, urinary tract infections, septicemia and intraabdominal infections, joint and bone infections, soft tissue and skin infections, typhoid fever, anthrax, bacterial gastroenteritis, urethral and gynecological infections, and pelvic inflammatory disease and several .